Tarun Kumar Bhatt, PhD

Publications:

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24. Rana, M., Pareek, A., Bhardwaj, S., Arya, G., Nimesh, S., Arya, H., Bhatt, T.K., Yaragorla, S. and Sharma, A.K. Aryldiazoquinoline based

      multifunctional small molecules for modulating Aβ 42 aggregation and cholinesterase activity related to Alzheimer's disease. RSC Advances, 10(48),

      pp.28827-28837, 2020 (IF-3.07).

23. Sharma D, Dada R, Tejavath KK, Rai P, Soni R, Yaragorla S, Bhatt TK. A paradigm towards the antimalarial quest: in silico identification and biological

      evaluation of novel inhibitors targeting 1-deoxy-D-xylulose-5-phosphate reductoisomerase. J Biomol Struct Dyn.,  27:17, 2020  (IF-3.1).

22. Pandey RK, Ali M, Ojha R, Bhatt TK, Prajapati VK. Developemt of multi-epitope driven subunit vaccine in secretory and membrane proteins of

      Plasmodium falciparum to convey protection against malaria infection. Vaccine, 36(30):4555, 2018  (IF-3.23).

21. Pandey RK , Sharma D, Ojha R, Bhatt TK, Prajapati VK. Chemical system biology based molecular interactions to identify inhibitors against Q151M   

      mutant of HIV-1 reverse transcriptase. Infect Genet Evol., 63:5-12, 2018 (IF-2.5).

20. Rajan Kumar Pandey, Bhatt TK, Vijay Kumar Prajapati. Novel Immunoinformatics Approaches to Design Multi-epitope Subunit Vaccine for Malaria by         

      Investigating Anopheles Salivary Protein.Sci. Rep., 2018 (IF-4.25).

19. Sharma D, Soni R, Rai P, Sharma B, Bhatt TK. Relict plastidic metabolic process as a potential therapeutic target. Drug Discovery Today, 2017

      (IF- 6.36 ).

18. Bhaskar Sharma & Bhatt TK. Genome-wide identification and expression analysis of E2 ubiquitin-conjugating enzymes in tomato. Sci. Rep.

      7(1):8631,2017 (IF-4.25).

17. Rani Soni, Drista Sharma, Praveen Rai, Bhaskar Sharma & Bhatt, T.K. Signaling Strategies of Malaria Parasite for Its Survival,

       Proliferation, and Infection during Erythrocytic Stage. Front. Immunol. March 2017 (IF-6.24)

16. Praveen Rai, Drista Sharma, Rani Soni, Nazia Khatton, Bhaskar Sharma & Bhatt, T.K. Plasmodium falciparum Apicoplast and Its

      Transcriptional Regulation Through Calcium Signalling. The Journal of Microbiology, 55(4):231-236, 2017 (IF-1.924)

15. Anuj Kumar, Drista Sharma…. & Bhatt, T.K. Cancer-testis antigens as molecular drug targets using network pharmacology. Tumor

      Biology. 1-9, 2016 (IF-2.926)

14. Drista Sharma, Rani Soni & Bhatt, T.K. In-silico studies on DegP protein of Plasmodium falciparum in search of anti-malarials. Journal

      of Molecular Modeling, 22:201, 2016 (IF-1.4)

13. Rajan kumar Pandey, Drista Sharma… Bhatt, T.K. & Vijay Kumar Prajapati. High-throughput virtual screening and quantum mechanics

      approach to develop imipramine analogues as leads against trypanothione reductase of Leishmania. Biomedicine & Pharmacotherapy,     

      83:141-152, 2016 (IF-2.3)

12. Bhaskar Sharma, Deepti Joshi, Pawan Yadav, Aditya kumar Gupta & Bhatt, T.K. Role of ubiquitin-mediated degradation system in plant 

      biology. Front. Plant Sci., 08 June 2016 (IF-4.45)

11. Bhatt, T.K., Rani Soni and Drista Sharma. Recent updates on DTD (D-Tyr-tRNATyr Deacylase): An enzyme essential for fidelity and quality

      of protein synthesis. Frontiers in Cell and Developmental Biology, 26 April 2016 (IF-DUE IN 2017)

10. Rani Soni, Drista Sharma & Bhatt, T.K. Plasmodium falciparum secretome in erythrocyte and beyond, Frontiers in Microbiology, Vol 7

      No. 00194, 2016 (IF-4.1)

9.   Rani Soni, Drista Sharma, Sachin Patel, Bhaskar Sharma & Bhatt, T.K. Structure based binding between protein farnesyl transferase and

      PRL-PTP of malaria parasite: An interaction study of prenylation process in Plasmodium, Journal of Biomolecular Structure and Dynamics,

      2016 (IF-3.1)

8.   Sachin Patel, Deepti Joshi, Rani Soni, Drista Sharma & Bhatt, T.K. Molecular modeling, in silico screening and molecular dynamics of

      PfPRL-PTP of P.falciparum for identification of potential anti-malarials, Journal of Biomolecular Structure and Dynamics, Sept 22:1-15, 2015

      (IF-3.1)

7.   Rajan Kumar Pandey, Drista Sharma, Bhatt, T.K. Shyam Sundar & Vijay Kumar Prajapati. Developing imidazole analogues as potential

      inhibitor for Leishmania donovani trypanothione reductase: virtual screening, molecular docking, dynamics and ADMET approach, Journal of

      Biomolecular Structure and Dynamics, Sept 28:1-13, 2015 (IF-3.1)

6.   Kalidhasan N, Joshi D, Bhatt, T.K. and Gupta AK. Identification of key genes involved in root development of tomato using expressed sequence tag

      analysis. Physiology and Molecular Biology of Plant, 21 (4):491-503, 2015 (IF-0.95)

5.   Bhatt, T.K. et al. Malaria parasite tyrosyl-tRNA synthetase upon secretion triggers pro-inflammatory responses. Nat. Commun. 8 (2):530, 2011

      (IF- 11.32)

4.   Bhatt, T.K. et al. Ligand-bound structure provide atomic snapshots for the catalytic mechanism of D-amino-acid deacylase. J Biol Chem.

      285(8):5917-30, 2010 (IF-4.57)

3.   Bhatt, T.K. et al. A genomic glimpse of aminoacyl-tRNA synthetases in malaria parasite Plasmodium falciparum. BMC Genomics. 31(10):644, 2009

      (IF-3.86)

2.   Yogavel M, Khan S, Bhatt, T.K. and Sharma A: Structure of native D-tyrosyl-tRNATyr deacylase by Iodide-SAD: structural polymorphism and HEPES

      bound enzyme states. Acta Crystallogr D Biol Crystallogr. 66(Pt 5):584-92, 2010 (IF-2.512)

1.  Goyal S, Arora S, Bhatt T.K., Das P, Sharma A, Kumari S, Arya D.S. Modulation of PPAR-gamma by telmisartan protects the heart against  

     myocardial infarction in experimental diabetes. Chem Biol Interact. 14;185(3):271-80, 2010 (IF-2.577)

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Books Edited

​1.  Studies on protein synthesis machinery of malaria parasite: Identification of new drug targets against malaria parasite by targeting protein synthesis machinery

     LAP Lambert Academic Publishing ( 2012); TK Bhatt;  ISBN: 9783659175749.

​2.  The design and development of novel drugs and vaccines: Principles and protocols; Academic Press, Elsevier (2021)

     TK Bhatt and Surendra Nimesh; ISBN- 9780128214718

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Book chapters

1.   H Arya, TK Bhatt. Role of Bioinformatics in Subunit Vaccine Design. Molecular Docking for Computer-Aided Drug Design: Fundamentals, Techniques,

      Resources and Applications (ISBN: 9780128223123) 425-439; https://doi.org/10.1016/B978-0-12-822312-3.00013-8, 2021.

2.   H Arya, MS Coumar, TK Bhatt. Introduction of structural bioinformatics with respect to drug discovery. The Design & Development of Novel Drugs and

      Vaccines: Principles and Protocols­ (ISBN: 9780128214718) 3-9; https://doi.org/10.1016/B978-0-12-821471-8.00001-5, 2021.

3.   H Arya, MS Coumar, TK Bhatt. Retrieval of compounds. The Design & Development of Novel Drugs and Vaccines: Principles and Protocols­

      (ISBN: 9780128214718) 21-29; https://doi.org/10.1016/B978-0-12-821471-8.00003-9, 2021.

4.   H Arya, TK Bhatt. Molecular dynamics simulations. The Design & Development of Novel Drugs and Vaccines: Principles and Protocols­

      (ISBN: 9780128214718) 65-81; https://doi.org/10.1016/B978-0-12-821471-8.00005-2, 2021.

5.   H Arya, TK Bhatt. An overview of vaccine design. The Design & Development of Novel Drugs and Vaccines: Principles and Protocols­

      (ISBN: 9780128214718) 85-91; https://doi.org/10.1016/B978-0-12-821471-8.00006-4, 2021.

6.   H Arya, TK Bhatt. Design of vaccine constructs. The Design & Development of Novel Drugs and Vaccines: Principles and Protocols

      (ISBN: 9780128214718) 109-119; https://doi.org/10.1016/B978-0-12-821471-8.00009-X, 2021.

7.   A Satapathy, TK Bhatt. Evaluation of immunogenicity of vaccine candidates. The Design & Development of Novel Drugs and Vaccines: Principles and

      Protocols­ (ISBN: 9780128214718) 233-238; https://doi.org/10.1016/B978-0-12-821471-8.00017-9, 2021.

8.   A Satapathy, TK Bhatt. In-vitro evaluation of lead molecule. The Design & Development of Novel Drugs and Vaccines: Principles and Protocols­

      (ISBN: 9780128214718) 239-245; https://doi.org/10.1016/B978-0-12-821471-8.00018-0, 2021.

9.   H Arya, MS Coumar, TK Bhatt. Brief introduction of clinical research and trials. The Design & Development of Novel Drugs and Vaccines: Principles    

      and Protocols­ (ISBN: 9780128214718) 263-266; https://doi.org/10.1016/B978-0-12-821471-8.000020-9, 2021.

10. H Arya, TK Bhatt. Introduction of intellectual property rights. The Design & Development of Novel Drugs and Vaccines: Principles and Protocols­

      (ISBN: 9780128214718) 275-281; https://doi.org/10.1016/B978-0-12-821471-8.000022-2, 2021.